Karmex DF is a long term non-selective herbicide for control of most annual and some perennial weeds and can be used for selective weed control in established apples, grapes, kiwifruit and asparagus. It is a dispersible granule to be mixed with water and applied as a spray for selective control of weeds in certain crops and for non-selective weed control on non-cropland areas . It is non-corrosive to equipment, non-flammable, and non-volatile. Karmex DF is a phenyl-urea herbicide and acts by inhibiting photosynthesis. It is only slightly soluble in water and is absorbed through the foliage and roots.

Karmex DF is a water dispersible granule (WG) that is to be mixed with water and applied as a spray for selective control of weeds in certain crops and for nonselective control of weeds in non-crop areas. This WG may be applied to the soil prior to emergence of the weeds to prevent emergence. Moisture is required to activate the product. Best results are obtained if rainfall occurs within two weeks of application.